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Reconstructing Folding Energy Landscapes by Single-Molecule Force Spectroscopy

Folding may be described conceptually in terms of trajectories over a landscape of free energies corresponding to different molecular configurations. In practice, energy landscapes can be difficult to measure. Single-molecule force spectroscopy (SMFS), whereby structural changes are monitored in mol...

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Publicat a:Annu Rev Biophys
Autors principals: Woodside, Michael T., Block, Steven M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609573/
https://ncbi.nlm.nih.gov/pubmed/24895850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-051013-022754
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