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Single-molecule force spectroscopy of the add adenine riboswitch relates folding to regulatory mechanism
Riboswitches regulate gene expression via ligand binding to an aptamer domain which induces conformational changes in a regulatory expression platform. By unfolding and refolding single add adenine riboswitch molecules in an optical trap, an integrated picture of the folding was developed and relate...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177178/ https://ncbi.nlm.nih.gov/pubmed/21653559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr305 |
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