Probing Position-Dependent Diffusion in Folding Reactions Using Single-Molecule Force Spectroscopy

Folding of proteins and nucleic acids involves a diffusive search over a multidimensional conformational energy landscape for the minimal-energy structure. When examining the projection of conformational motions onto a one-dimensional reaction coordinate, as done in most experiments, the diffusion c...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Foster, Daniel A.N., Petrosyan, Rafayel, Pyo, Andrew G.T., Hoffmann, Armin, Wang, Feng, Woodside, Michael T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2018
Soggetti:
Molecular Machines, Motors, and Nanoscale Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954564/
https://ncbi.nlm.nih.gov/pubmed/29642035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.02.026
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