Determining Intrachain Diffusion Coefficients for Biopolymer Dynamics from Single-Molecule Force Spectroscopy Measurements

The conformational diffusion coefficient for intrachain motions in biopolymers, D, sets the timescale for structural dynamics. Recently, force spectroscopy has been applied to determine D both for unfolded proteins and for the folding transitions in proteins and nucleic acids. However, interpretatio...

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Bibliographic Details
Main Authors: Woodside, Michael T., Lambert, John, Beach, Kevin S.D.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2014
Subjects:
Molecular Machines, Motors and Nanoscale Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190644/
https://ncbi.nlm.nih.gov/pubmed/25296317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.08.007
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