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The Fundamental Difficulty With Evaluating the Accuracy of Biomarkers for Guiding Treatment

Developing biomarkers that can predict whether patients are likely to benefit from an intervention is a pressing objective in many areas of medicine. Recent guidance documents have recommended that the accuracy of predictive biomarkers, ie, sensitivity, specificity, and positive and negative predict...

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Detalles Bibliográficos
Publicado en:J Natl Cancer Inst
Main Authors: Janes, Holly, Pepe, Margaret S., McShane, Lisa M., Sargent, Daniel J., Heagerty, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609557/
https://ncbi.nlm.nih.gov/pubmed/26109106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv157
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