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Biomarkers in early-phase trials: fundamental issues

Biomarkers are frequently being included in early-phase clinical trials. This article is meant to introduce clinical investigators to the fundamentals of choosing a biomarker test for use in an early phase trial. Steps to consider are briefly outlined including defining the role of the biomarker in...

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Détails bibliographiques
Publié dans:Bioanalysis
Auteurs principaux: Yee, Laura M, Lively, Tracy G, McShane, Lisa M
Format: Artigo
Langue:Inglês
Publié: Future Science Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123886/
https://ncbi.nlm.nih.gov/pubmed/29923753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio-2018-0006
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