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Alternative Hfq-sRNA interaction modes dictate alternative mRNA recognition
Many bacteria use small RNAs (sRNAs) and the RNA chaperone Hfq to regulate mRNA stability and translation. Hfq, a ring-shaped homohexamer, has multiple faces that can bind both sRNAs and their mRNA targets. We find that Hfq has at least two distinct ways in which it interacts with sRNAs; these diffe...
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| Publicado en: | EMBO J |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609186/ https://ncbi.nlm.nih.gov/pubmed/26373314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591569 |
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