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Alternative Hfq-sRNA interaction modes dictate alternative mRNA recognition

Many bacteria use small RNAs (sRNAs) and the RNA chaperone Hfq to regulate mRNA stability and translation. Hfq, a ring-shaped homohexamer, has multiple faces that can bind both sRNAs and their mRNA targets. We find that Hfq has at least two distinct ways in which it interacts with sRNAs; these diffe...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Schu, Daniel J, Zhang, Aixia, Gottesman, Susan, Storz, Gisela
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609186/
https://ncbi.nlm.nih.gov/pubmed/26373314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591569
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