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Mutations in interaction surfaces differentially impact E. coli Hfq association with small RNAs and their mRNA targets

The RNA chaperone protein Hfq is required for the function of all small RNAs (sRNAs) that regulate mRNA stability or translation by limited base pairing in E. coli. While there have been numerous in vitro studies to characterize Hfq activity and the importance of specific residues, there has been on...

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Detalhes bibliográficos
Main Authors: Zhang, Aixia, Schu, Daniel J., Tjaden, Brian C., Storz, Gisela, Gottesman, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640674/
https://ncbi.nlm.nih.gov/pubmed/23318956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.01.006
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