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Major role for mRNA binding and restructuring in sRNA recruitment by Hfq
Bacterial small RNAs (sRNAs) modulate gene expression by base-pairing with target mRNAs. Many sRNAs require the Sm-like RNA binding protein Hfq as a cofactor. Well-characterized interactions between DsrA sRNA and the rpoS mRNA leader were used to understand how Hfq stimulates sRNA pairing with targe...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3153977/ https://ncbi.nlm.nih.gov/pubmed/21705431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2767211 |
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