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Major role for mRNA binding and restructuring in sRNA recruitment by Hfq

Bacterial small RNAs (sRNAs) modulate gene expression by base-pairing with target mRNAs. Many sRNAs require the Sm-like RNA binding protein Hfq as a cofactor. Well-characterized interactions between DsrA sRNA and the rpoS mRNA leader were used to understand how Hfq stimulates sRNA pairing with targe...

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Detalhes bibliográficos
Main Authors: Soper, Toby J., Doxzen, Kevin, Woodson, Sarah A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153977/
https://ncbi.nlm.nih.gov/pubmed/21705431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2767211
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