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Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen
Vinculin is filamentous (F)-actin-binding protein enriched in integrin-based adhesions to the extracellular matrix (ECM). Whereas studies in 2-dimensional (2D) tissue culture models have suggested that vinculin negatively regulates cell migration by promoting cytoskeleton–ECM coupling to strengthen...
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| 出版年: | FASEB J |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Federation of American Societies for Experimental Biology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608908/ https://ncbi.nlm.nih.gov/pubmed/26195589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-268235 |
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