Inherited human group IVA cytosolic phospholipase A(2) deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation

Eicosanoids are important vascular regulators, but the phospholipase A(2) (PLA(2)) isoforms supporting their production within the cardiovascular system are not fully understood. To address this, we have studied platelets, endothelial cells, and leukocytes from 2 siblings with a homozygous loss-of-f...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:FASEB J
Κύριοι συγγραφείς: Kirkby, Nicholas S., Reed, Daniel M., Edin, Matthew L., Rauzi, Francesca, Mataragka, Stefania, Vojnovic, Ivana, Bishop-Bailey, David, Milne, Ginger L., Longhurst, Hilary, Zeldin, Darryl C., Mitchell, Jane A., Warner, Timothy D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Federation of American Societies for Experimental Biology 2016
Θέματα:
Research Communication
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608906/
https://ncbi.nlm.nih.gov/pubmed/26183771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-275065
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