Inherited human group IVA cytosolic phospholipase A(2) deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation

Eicosanoids are important vascular regulators, but the phospholipase A(2) (PLA(2)) isoforms supporting their production within the cardiovascular system are not fully understood. To address this, we have studied platelets, endothelial cells, and leukocytes from 2 siblings with a homozygous loss-of-f...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:FASEB J
المؤلفون الرئيسيون: Kirkby, Nicholas S., Reed, Daniel M., Edin, Matthew L., Rauzi, Francesca, Mataragka, Stefania, Vojnovic, Ivana, Bishop-Bailey, David, Milne, Ginger L., Longhurst, Hilary, Zeldin, Darryl C., Mitchell, Jane A., Warner, Timothy D.
التنسيق: Artigo
اللغة:Inglês
منشور في: Federation of American Societies for Experimental Biology 2016
الموضوعات:
Research Communication
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608906/
https://ncbi.nlm.nih.gov/pubmed/26183771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-275065
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