Synthetic Oligodeoxynucleotides Containing Multiple Telemeric TTAGGG Motifs Suppress Inflammasome Activity in Macrophages Subjected to Oxygen and Glucose Deprivation and Reduce Ischemic Brain Injury in Stroke-Prone Spontaneously Hypertensive Rats

The immune system plays a fundamental role in both the development and pathobiology of stroke. Inflammasomes are multiprotein complexes that have come to be recognized as critical players in the inflammation that ultimately contributes to stroke severity. Inflammasomes recognize microbial and host-d...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Zhao, Jing, Mou, Yongshan, Bernstock, Joshua D., Klimanis, Dace, Wang, Sixian, Spatz, Maria, Maric, Dragan, Johnson, Kory, Klinman, Dennis M., Li, Xiaohong, Li, Xinhui, Hallenbeck, John M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608557/
https://ncbi.nlm.nih.gov/pubmed/26473731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140772
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