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‘PEAR-ing’ Genomic and Epigenomic Analyses for Cancer Gene Discovery

Somatic structural variants in tumor genomes can deregulate transcription through repositioning of enhancer elements. A new method, PEAR-ChIP, leverages paired-end H3K27ac ChIP-seq and current current computational methods to identify such events.

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Discov
Egile Nagusiak: Mack, Stephen C., Rich, Jeremy N., Scacheri, Peter C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608252/
https://ncbi.nlm.nih.gov/pubmed/26429935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0985
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