Personalized genomic analyses for cancer mutation discovery and interpretation

Massively parallel sequencing approaches are beginning to be used clinically to characterize individual patient tumors and to select therapies based on the identified mutations. A major question in these analyses is the extent to which these methods identify clinically actionable alterations and whe...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Jones, Siân, Anagnostou, Valsamo, Lytle, Karli, Parpart-Li, Sonya, Nesselbush, Monica, Riley, David R., Shukla, Manish, Chesnick, Bryan, Kadan, Maura, Papp, Eniko, Galens, Kevin G., Murphy, Derek, Zhang, Theresa, Kann, Lisa, Sausen, Mark, Angiuoli, Samuel V., Diaz, Luis A., Velculescu, Victor E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442685/
https://ncbi.nlm.nih.gov/pubmed/25877891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa7161
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