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Personalized genomic analyses for cancer mutation discovery and interpretation

Massively parallel sequencing approaches are beginning to be used clinically to characterize individual patient tumors and to select therapies based on the identified mutations. A major question in these analyses is the extent to which these methods identify clinically actionable alterations and whe...

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Bibliografski detalji
Izdano u:Sci Transl Med
Glavni autori: Jones, Siân, Anagnostou, Valsamo, Lytle, Karli, Parpart-Li, Sonya, Nesselbush, Monica, Riley, David R., Shukla, Manish, Chesnick, Bryan, Kadan, Maura, Papp, Eniko, Galens, Kevin G., Murphy, Derek, Zhang, Theresa, Kann, Lisa, Sausen, Mark, Angiuoli, Samuel V., Diaz, Luis A., Velculescu, Victor E.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442685/
https://ncbi.nlm.nih.gov/pubmed/25877891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa7161
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