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Interplay Between the Cancer Genome and Epigenome

Cancer arises as a consequence of cumulative disruptions to cellular growth control, with Darwinian selection for those heritable changes which provide the greatest clonal advantage. These traits can be acquired and stably maintained by either genetic or epigenetic means. Here we explore the ways in...

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Detalhes bibliográficos
Main Authors: Shen, Hui, Laird, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648790/
https://ncbi.nlm.nih.gov/pubmed/23540689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.03.008
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