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‘PEAR-ing’ Genomic and Epigenomic Analyses for Cancer Gene Discovery
Somatic structural variants in tumor genomes can deregulate transcription through repositioning of enhancer elements. A new method, PEAR-ChIP, leverages paired-end H3K27ac ChIP-seq and current current computational methods to identify such events.
Gardado en:
| Publicado en: | Cancer Discov |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608252/ https://ncbi.nlm.nih.gov/pubmed/26429935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0985 |
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