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A Phase I/II adaptive design for heterogeneous groups with application to a stereotactic body radiation therapy trial
Dose-finding studies that aim to evaluate the safety of single agents are becoming less common, and advances in clinical research have complicated the paradigm of dose finding in oncology. A class of more complex problems, such as targeted agents, combination therapies and stratification of patients...
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| Wydane w: | Pharm Stat |
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| Główni autorzy: | , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608237/ https://ncbi.nlm.nih.gov/pubmed/25962576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1686 |
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