A gene regulatory network cooperatively controlled by Pdx1 and Sox9 governs lineage allocation of foregut progenitor cells

The generation of pancreas, liver and intestine from a common pool of progenitors in the foregut endoderm requires the establishment of organ boundaries. How dorsal foregut progenitors activate pancreatic genes and evade the intestinal lineage choice remains unclear. We here identify Pdx1 and Sox9 a...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Shih, Hung Ping, Seymour, Philip A., Patel, Nisha A., Xie, Ruiyu, Wang, Allen, Liu, Patrick P., Yeo, Gene W., Magnuson, Mark A., Sander, Maike
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607666/
https://ncbi.nlm.nih.gov/pubmed/26440894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.082
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