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ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage Recognition

Resolution of DNA double-strand breaks (DSBs) is essential for the suppression of genome instability. DSB repair in transcriptionally active genomic regions represents a unique challenge that is associated with an Ataxia telangiectasia mutated (ATM) kinase-mediated transcriptional silencing. Despite...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Harding, Shane M, Boiarsky, Jonathan A, Greenberg, Roger A
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607662/
https://ncbi.nlm.nih.gov/pubmed/26440899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.085
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