Syntheses and evaluation of substituted aromatic hydroxamates and hydroxamic acids that target mycobacterium tuberculosis

Tuberculosis (TB) continues to remain one of the most threatening diseases in the world. With the emergence of multi-drug resistant (MDR) and extensively drug resistant (XDR) strains, the need to develop new therapies is dire. The syntheses of a focused library of hydroxamates and hydroxamic acids i...

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Veröffentlicht in:Bioorg Med Chem Lett
Hauptverfasser: Majewski, Mark W., Cho, Sanghyun, Miller, Patricia A., Franzblau, Scott G., Miller, Marvin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607592/
https://ncbi.nlm.nih.gov/pubmed/26037320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.04.099
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