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Syntheses and evaluation of substituted aromatic hydroxamates and hydroxamic acids that target mycobacterium tuberculosis

Tuberculosis (TB) continues to remain one of the most threatening diseases in the world. With the emergence of multi-drug resistant (MDR) and extensively drug resistant (XDR) strains, the need to develop new therapies is dire. The syntheses of a focused library of hydroxamates and hydroxamic acids i...

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Bibliografiske detaljer
Udgivet i:Bioorg Med Chem Lett
Main Authors: Majewski, Mark W., Cho, Sanghyun, Miller, Patricia A., Franzblau, Scott G., Miller, Marvin J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607592/
https://ncbi.nlm.nih.gov/pubmed/26037320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.04.099
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