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Syntheses and Biological Evaluations of Highly Functionalized Hydroxamate Containing and N-Methylthio Monobactams as Anti-Tuberculosis and β-Lactamase Inhibitory Agents

Both the resurgence of tuberculosis (TB) and antibiotic resistance continue to threaten modern healthcare and new means of combating pathogenic bacterial infections are needed. The syntheses of monobactams possessing hydroxamate and N-methylthio functionality are described, as well as their anti-TB,...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Majewski, Mark W., Watson, Kyle D., Cho, Sanghyun, Miller, Patricia A., Franzblau, Scott G., Miller, Marvin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762374/
https://ncbi.nlm.nih.gov/pubmed/26918106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5MD00340G
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