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Syntheses and Studies of New Forms of N-Sulfonyloxy β-Lactams as Potential Antibacterial Agents and β-Lactamase Inhibitors
The synthesis of a small library of N-sulfonyloxy-2-azetidinones is reported and the preliminary results of the investigation of the biological activity of these molecules are discussed. These new multi-electrophilic β-lactams (“electrophilic bombs”) display unexpected selectivity in their antibacte...
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| Yayımlandı: | Bioorg Med Chem |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4562877/ https://ncbi.nlm.nih.gov/pubmed/26321604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.08.005 |
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