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Syntheses of Mycobactin Analogs as Potent and Selective Inhibitors of Mycobacterium tuberculosis
Three analogs of mycobactin T, the siderophore secreted by Mycobacterium tuberculosis (Mtb) were synthesized and screened for their antibiotic activity against Mtb H(37)Rv and a broad panel of Gram-positive and Gram-negative bacteria. The synthetic mycobactins were potent (MIC(90) 0.02–0.88 μM in 7H...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482464/ https://ncbi.nlm.nih.gov/pubmed/22895786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ob26077h |
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