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Syntheses of Mycobactin Analogs as Potent and Selective Inhibitors of Mycobacterium tuberculosis

Three analogs of mycobactin T, the siderophore secreted by Mycobacterium tuberculosis (Mtb) were synthesized and screened for their antibiotic activity against Mtb H(37)Rv and a broad panel of Gram-positive and Gram-negative bacteria. The synthetic mycobactins were potent (MIC(90) 0.02–0.88 μM in 7H...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Juárez-Hernández, Raúl E., Franzblau, Scott G., Miller, Marvin J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482464/
https://ncbi.nlm.nih.gov/pubmed/22895786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ob26077h
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