Large-Scale Purification of r28M: A Bispecific scFv Antibody Targeting Human Melanoma Produced in Transgenic Cattle

BACKGROUND: 30 years ago, the potential of bispecific antibodies to engage cytotoxic T cells for the lysis of cancer cells was discovered. Today a variety of bispecific antibodies against diverse cell surface structures have been developed, the majority of them produced in mammalian cell culture sys...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Spiesberger, Katrin, Paulfranz, Florian, Egger, Anton, Reiser, Judith, Vogl, Claus, Rudolf-Scholik, Judith, Mayrhofer, Corina, Grosse-Hovest, Ludger, Brem, Gottfried
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607477/
https://ncbi.nlm.nih.gov/pubmed/26469402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140471
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