Characterization and analysis of scFv-IgG bispecific antibody size variants

Bispecific antibodies are an emergent class of biologics that is of increasing interest for therapeutic applications. In one bispecific antibody format, single-chain variable fragments (scFv) are linked to or inserted in different locations of an intact immunoglobulin G (IgG) molecule to confer dual...

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Vydáno v:MAbs
Hlavní autoři: Cao, Mingyan, Wang, Chunlei, Chung, Wai Keen, Motabar, Dana, Wang, Jihong, Christian, Elizabeth, Lin, Shihua, Hunter, Alan, Wang, Xiangyang, Liu, Dengfeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284595/
https://ncbi.nlm.nih.gov/pubmed/30130449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1505398
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