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Antroquinonol Lowers Brain Amyloid-β Levels and Improves Spatial Learning and Memory in a Transgenic Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common form of dementia. The deposition of brain amyloid-β peptides (Aβ), which are cleaved from amyloid precursor protein (APP), is one of the pathological hallmarks of AD. Aβ-induced oxidative stress and neuroinflammation play important roles in the pathogenesi...

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Pubblicato in:Sci Rep
Autori principali: Chang, Wen-Han, Chen, Miles C., Cheng, Irene H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606808/
https://ncbi.nlm.nih.gov/pubmed/26469245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15067
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