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Retinoic Acid Attenuates β-Amyloid Deposition and Rescues Memory Deficits in an Alzheimer's Disease Transgenic Mouse Model
Recent studies have revealed that disruption of vitamin A signaling observed in Alzheimer's disease (AD) leads to β-amyloid (Aβ) accumulation and memory deficits in rodents. The aim of the present study was to evaluate the therapeutic effect of all-trans retinoic acid (ATRA), an active metaboli...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Society for Neuroscience
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844785/ https://ncbi.nlm.nih.gov/pubmed/18987198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3153-08.2008 |
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