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Prion protein antagonists rescue Alzheimer’s amyloid-beta-related cognitive deficits

Recent studies revealed that cellular prion protein on neurons bind Alzheimer’s amyloid-beta oligomers causing neurotoxic effects. A new article in Cell Reports by Gunther and colleagues shows that an orally administered cellular prion protein antagonist can rescue synaptic and cognitive deficits in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Trends Mol Med
Päätekijät: Sagare, Abhay P., Sweeney, Melanie D., Nelson, Amy R., Zhao, Zhen, Zlokovic, Berislav V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377285/
https://ncbi.nlm.nih.gov/pubmed/30661727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2019.01.001
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