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Blood–brain barrier breakdown in Alzheimer’s disease and other neurodegenerative disorders

The blood–brain barrier (BBB) is a continuous endothelial membrane within brain microvessels that has sealed cell-to-cell contacts, and is sheathed by mural vascular cells and perivascular astrocyte end-feet. The BBB protects neurons from factors present in the systemic circulation, and maintains th...

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Dades bibliogràfiques
Publicat a:Nat Rev Neurol
Autors principals: Sweeney, Melanie D., Sagare, Abhay P., Zlokovic, Berislav V.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829048/
https://ncbi.nlm.nih.gov/pubmed/29377008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2017.188
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