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Blood–brain barrier breakdown in Alzheimer’s disease and other neurodegenerative disorders
The blood–brain barrier (BBB) is a continuous endothelial membrane within brain microvessels that has sealed cell-to-cell contacts, and is sheathed by mural vascular cells and perivascular astrocyte end-feet. The BBB protects neurons from factors present in the systemic circulation, and maintains th...
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| Publicado no: | Nat Rev Neurol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5829048/ https://ncbi.nlm.nih.gov/pubmed/29377008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2017.188 |
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