A New Chiral Pyrrolyl α-Nitronyl Nitroxide Radical Attenuates β-Amyloid Deposition and Rescues Memory Deficits in a Mouse Model of Alzheimer Disease

The generation of reactive oxygen species causes cellular oxidative damage, and has been implicated in the etiology of Alzheimer’s disease (AD). L-NNNBP, a new chiral pyrrolyl α-nitronyl nitroxide radical synthesized in our department, shows potential antioxidant effects. The purpose of this study w...

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Detalhes bibliográficos
Main Authors: Shi, Tian-yao, Zhao, Da-qing, Wang, Hai-bo, Feng, Shufang, Liu, Shui-bing, Xing, Jiang-hao, Qu, Yang, Gao, Peng, Sun, Xiao-li, Zhao, Ming-gao
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625382/
https://ncbi.nlm.nih.gov/pubmed/23212232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-012-0168-z
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