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Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets
MicroRNAs (miRNAs) direct post-transcriptional regulation of human genes by guiding Argonaute proteins to complementary sites in messenger RNAs (mRNAs) targeted for repression. An enigmatic feature of many conserved mammalian miRNA target sites is that an adenosine (A) nucleotide opposite miRNA nucl...
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| Publié dans: | eLife |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4606517/ https://ncbi.nlm.nih.gov/pubmed/26359634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07646 |
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