Prostate-Cancer-Targeted N-(2-Hydroxypropyl)methacrylamide Copolymer/Docetaxel Conjugates

Biodistribution, pharmacokinetics, and efficacy of prostate-cancer-targeted HPMA copolymer/DTX conjugates are evaluated in nude mice bearing prostate cancer C4-2 xenografts. PSMA-specific monoclonal antibodies 3F/11 are used as the targeting moiety. Control conjugates contain either non-specific IgG...

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Bibliografski detalji
Izdano u:Macromol Biosci
Glavni autori: Liu, Jihua, Kopečková, Pavla, Pan, Huaizhong, Sima, Monika, Bühler, Patrick, Wolf, Philipp, Elsässer-Beile, Ursula, Kopeček, Jindřich
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605348/
https://ncbi.nlm.nih.gov/pubmed/22493797
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