Backbone Degradable Multiblock N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates via Reversible Addition Fragmentation Chain Transfer Polymerization and Thiol-ene Coupling Reaction

Telechelic water-soluble HPMA copolymers and HPMA copolymer-doxorubicin (DOX) conjugates have been synthesized by RAFT polymerization mediated by a new bifunctional chain transfer agent (CTA) that contains an enzymatically degradable oligopeptide sequence. Post-polymerization aminolysis followed by...

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Detaylı Bibliyografya
Asıl Yazarlar: Pan, Huaizhong, Yang, Jiyuan, Kopečková, Pavla, Kopeček, Jindřich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025662/
https://ncbi.nlm.nih.gov/pubmed/21158387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm101254e
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