Release of Prostaglandin E(1) from N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates by Bone Cells

Bone-targeting N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-PGE(1) conjugates, containing cathepsin K sensitive spacers, were incubated with induced osteoclasts and osteoblasts, their precursors, and control non-skeletal cells. The release of PGE(1) was monitored by an HPLC assay. In both muri...

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Bibliografiska uppgifter
I publikationen:Macromol Biosci
Huvudupphovsmän: Pan, Huaizhong, Liu, Jihua, Dong, Yuanyi, Sima, Monika, Kopečková, Pavla, Brandi, Maria Luisa, Kopeček, Jindřich
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605216/
https://ncbi.nlm.nih.gov/pubmed/18401866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.200700338
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