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Release of Prostaglandin E(1) from N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates by Bone Cells
Bone-targeting N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-PGE(1) conjugates, containing cathepsin K sensitive spacers, were incubated with induced osteoclasts and osteoblasts, their precursors, and control non-skeletal cells. The release of PGE(1) was monitored by an HPLC assay. In both muri...
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| Udgivet i: | Macromol Biosci |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4605216/ https://ncbi.nlm.nih.gov/pubmed/18401866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.200700338 |
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