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Sequential combination therapy of ovarian cancer with degradable N-(2-hydroxypropyl)methacrylamide copolymer paclitaxel and gemcitabine conjugates

For rapid and effective clinical translation, polymer-based anticancer therapeutics need long circulating conjugates that produce a sustained concentration gradient between the vasculature and solid tumor. To this end, we designed second-generation backbone-degradable diblock N-(2-hydroxypropyl)meth...

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Detalhes bibliográficos
Main Authors: Zhang, Rui, Yang, Jiyuan, Sima, Monika, Zhou, Yan, Kopeček, Jindřich
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143033/
https://ncbi.nlm.nih.gov/pubmed/25092316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406233111
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