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Combination cytotoxicity of backbone degradable HPMA copolymer gemcitabine and platinum conjugates toward human ovarian carcinoma cells
Multiblock, backbone degradable HPMA copolymer-drug conjugates containing gemcitabine and DACH platinum (mP-GEM and mP-DACH Pt), respectively were synthesized by reversible addition fragmentation (RAFT) polymerization and subsequent chain extension by click chemistry. Using combination index analysi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035385/ https://ncbi.nlm.nih.gov/pubmed/24316339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2013.11.008 |
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