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FRET-trackable biodegradable HPMA copolymer-epirubicin conjugates for ovarian carcinoma therapy
To develop a biodegradable polymeric drug delivery system for the treatment of ovarian cancer with the capacity for non-invasive fate monitoring, we designed and synthesized N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-epirubicin (EPI) conjugates. The polymer backbone was labeled with acceptor...
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| Publicado no: | J Control Release |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631633/ https://ncbi.nlm.nih.gov/pubmed/26410808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.045 |
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