FRET-trackable biodegradable HPMA copolymer-epirubicin conjugates for ovarian carcinoma therapy

To develop a biodegradable polymeric drug delivery system for the treatment of ovarian cancer with the capacity for non-invasive fate monitoring, we designed and synthesized N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-epirubicin (EPI) conjugates. The polymer backbone was labeled with acceptor...

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Bibliografske podrobnosti
izdano v:J Control Release
Main Authors: Yang, Jiyuan, Zhang, Rui, Radford, D. Christopher, Kopeček, Jindřich
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631633/
https://ncbi.nlm.nih.gov/pubmed/26410808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.045
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