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N-(2-Hydroxypropyl)methacrylamide Copolymer-drug Conjugates for Combination Chemotherapy of Acute Myeloid Leukemia

There is a need for new treatment strategies of acute myeloid leukemia (AML). In this study, four different drugs, including cytarabine, daunorubicin, GDC-0980 and JS-K, were investigated in vitro using HL-60 cells for the treatment of AML. Two-drug combinations were studied in order to maximize the...

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Publicado en:Macromol Biosci
Main Authors: Zhang, Rui, Yang, Jiyuan, Zhou, Yan, Shami, Paul J., Kopeček, Jindřich
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805371/
https://ncbi.nlm.nih.gov/pubmed/26222892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201500193
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