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A conserved Polϵ binding module in Ctf18-RFC is required for S-phase checkpoint activation downstream of Mec1
Defects during chromosome replication in eukaryotes activate a signaling pathway called the S-phase checkpoint, which produces a multifaceted response that preserves genome integrity at stalled DNA replication forks. Work with budding yeast showed that the ‘alternative clamp loader’ known as Ctf18-R...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4605302/ https://ncbi.nlm.nih.gov/pubmed/26250113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv799 |
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