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Surviving chromosome replication: the many roles of the S-phase checkpoint pathway

Checkpoints were originally identified as signalling pathways that delay mitosis in response to DNA damage or defects in chromosome replication, allowing time for DNA repair to occur. The ATR (ataxia- and rad-related) and ATM (ataxia-mutated) protein kinases are recruited to defective replication fo...

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Detalhes bibliográficos
Main Authors: Labib, Karim, De Piccoli, Giacomo
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203454/
https://ncbi.nlm.nih.gov/pubmed/22084382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0071
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