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Surviving chromosome replication: the many roles of the S-phase checkpoint pathway
Checkpoints were originally identified as signalling pathways that delay mitosis in response to DNA damage or defects in chromosome replication, allowing time for DNA repair to occur. The ATR (ataxia- and rad-related) and ATM (ataxia-mutated) protein kinases are recruited to defective replication fo...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203454/ https://ncbi.nlm.nih.gov/pubmed/22084382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0071 |
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