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A Role for Jag2 in Promoting Uveal Melanoma Dissemination and Growth

PURPOSE. Controlling the spread of uveal melanoma is key to improving survival of patients with this common intraocular malignancy. The Notch ligand Jag2 has been shown to be upregulated in primary tumors that metastasize, and we therefore investigated its role in promoting invasion and clonogenic g...

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Pubblicato in:Invest Ophthalmol Vis Sci
Autori principali: Asnaghi, Laura, Handa, James T., Merbs, Shannath L., Harbour, J. William, Eberhart, Charles G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604713/
https://ncbi.nlm.nih.gov/pubmed/23211831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10209
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