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A Role for Jag2 in Promoting Uveal Melanoma Dissemination and Growth

PURPOSE. Controlling the spread of uveal melanoma is key to improving survival of patients with this common intraocular malignancy. The Notch ligand Jag2 has been shown to be upregulated in primary tumors that metastasize, and we therefore investigated its role in promoting invasion and clonogenic g...

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Bibliografske podrobnosti
izdano v:Invest Ophthalmol Vis Sci
Main Authors: Asnaghi, Laura, Handa, James T., Merbs, Shannath L., Harbour, J. William, Eberhart, Charles G.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604713/
https://ncbi.nlm.nih.gov/pubmed/23211831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10209
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